Genome Editing and Engine
CRISPR technology is frequently leveraged for reversible gene knockdown, through CRISPR interference (CRISPRi) and gain-of-function gene knockin approaches are made possible by the CRISPR/Cas9 system as well. The precision and relative simplicity of the CRISPR gene editing system has enabled scientists to modify DNA quickly and efficiently in both engineered cell lines and mouse models, with a wide range of possible applications across research areas, target genomes, and industries. Gene editing has the potential to revolutionize genetic approaches to personalized medicine, and could enable a new era of gene-based therapeutic treatment options for heretofore untreatable diseases.
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